Oncology In Vivo Data Integration for Hypothesis Generation
نویسندگان
چکیده
AstraZeneca's Oncology in vivo data integration platform brings multidimensional data from animal model efficacy, pharmacokinetic and pharmacodynamic data to animal model profiling data and public in vivo studies. Using this platform, scientists can cluster model efficacy and model profiling data together, quickly identify responder profiles and correlate molecular characteristics to pharmacological response. Through meta-analysis, scientists can compare pharmacology between single and combination treatments, between different drug scheduling and administration routes.
منابع مشابه
Absorbed Dose Calculation In Irregular Blocked Radiation Fields: Evaluation of Clarkson’s Sector Integration Method for Radiation Fields Commonly Used in Conventional Radiotherapy
Introduction: Irregular/blocked fields are routinely used in radiotherapy. The doses of these fields are usually calculated by means of equivalent square method that is inherently prone to uncertainty. On the other hand, Clarkson’s sector integration method is a dose calculation method which offers far better accuracy in dose calculation of irregular fields. The Scatter Air Ratio (SAR) of an in...
متن کاملThe Effect of Motor Dependent/Independent Visual Perception Training on Visual-Motor Integration and Fine Motor Skills of 7-8-year-old Children: The Retest of Movement Hypothesis
The purpose of this study was to examine the effect of motor dependent/independent visual perception training on visual-motor integration and fine motor skills of 7-8 year old children .For this purpose, 107, 1st grade primary school students in Sabzevar were selected through purposive sampling (with equal economical and cultural status , optimum mental and physical health and full sight with...
متن کاملThe Impact of Integration on International Trade Flows: the Cases of EU, OIC & ECO
The growth of regional trade blocks has been one of the major developments in international relations in recent years. Regional agreements vary widely but, all have the objective of reducing barriers to trade between member countries that in most cases result in increasingly trade flows and economic growth. This paper attempts to explore the results of trade integration in ECO, EU and OIC block...
متن کاملMulti Objective Scheduling of Utility-scale Energy Storages and Demand Response Programs Portfolio for Grid Integration of Wind Power
Increasing the penetration of variable wind generation in power systems has created some new challenges in the power system operation. In such a situation, the inclusion of flexible resources which have the potential of facilitating wind power integration is necessary. Demand response (DR) programs and emerging utility-scale energy storages (ESs) are known as two powerful flexible tools that ca...
متن کاملAssessment of a 2D EPID-based Dosimetry Algorithm for Pre-treatment and In-vivo Midplane Dose Verification
Introduction: The use of electronic portal imaging devices (EPIDs) is a method for the dosimetric verification of radiotherapy plans both pretreatment and in-vivo. The aim of this study was to test a 2D EPID-based dosimetry algorithm for dose verification of some plans inside a homogenous and anthropomorphic phantom and in-vivo, as well. Materials and Methods: </strong...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Journal of integrative bioinformatics
دوره 9 2 شماره
صفحات -
تاریخ انتشار 2012